1
Return

Bivalent gambogic acid-functionalized curcumin nanoparticles with insulin modulate the gut-liver-kidney network in type 2 diabetes

delete2026-07-30
delete0
PRE
AI
S
Swetha R. Allamreddy
R
Raghu Ganugula
A
Alejandro Gonzalez
M
Meenakshi Arora
R
Richard Friend
M
M. N. V. Ravi Kumar *
DOI：10.1016/j.jconrel.2026.115224delete
deleteOriginal
deleteOriginal request for help
deleteShare
deleteSave
Abstract

Abstract

En 中文
• Oral nGA2-CUR enhance systemic curcumin bioavailability. • nGA2-CUR and insulin stabilize the GLK network in T2DM. • Combinatorial therapy manages the endocrine burden and multi-organ pathology. • nGA2-CUR reshapes gut microbiome via distinct sex-specific bacterial signatures. • Upstream metabolic and microbial resolution attenuates downstream renal fibrosis.

Journal

Journal of Controlled Release cover
Journal of Controlled Release
IF:
11.5
Papers:
1.5W
Citations:
7.4W

Organization

T
The University of Alabama
Scholars:
561
Papers: 241
Citations: 1
Cited Papers

Cited Papers

Citing Papers

Citing Papers