.png){kind=icon}
.png){kind=icon}
Return
Brain microstructural alterations on quantitative synthetic MRI and correlation with cognitive dysfunction in patients with β-thalassemia major
.png){kind=icon}
OA
AI
M
X
X
H
L
B
W
M
B
DOI：10.1016/j.brainresbull.2026.111917.png)
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• Patients with β-thalassemia major (β-TM) often exhibit cognitive impairment, but the underlying brain microstructural alterations remain unclear and lack objective neuroimaging evidence. • Quantitative SyMRI revealed both decreased and increased T1 values in gray and white matter regions, which correlated with cognitive decline and hematological abnormalities in β-TM. • This study highlights the potential of SyMRI as a non-invasive imaging tool for early detection of cognitive dysfunction in β-TM, aiding timely clinical intervention.
Keywords:
Beta-thalassemia major
quantitative synthetic MRI
brain gray matter microstructure
white matter alterations
cognitive function
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
3.7
Papers:
6.8K
Citations:
1.2W
Organization
Cited Papers