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Brain structure in the cingulate cortex and locus coeruleus in late life is associated with engagement in complex mental activities across the life span
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DOI：10.1016/j.neurobiolaging.2026.06.012.png)
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Abstract
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• Life span engagement in complex activities is related to brain health in late life. • Early life activities were associated with greater cingulate volume and thickness. • Late life activities were associated with higher integrity of the locus coeruleus.
Keywords:
Gray matter volume
Cortical thickness
Enrichment
Mentally stimulating activities
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