.png){kind=icon}
Return
Brainstem Circuits Controlling Action Diversification
.png){kind=icon}
OA
AI
DOI：10.1146/annurev-neuro-070918-050201.png)
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
Neuronal circuits that regulate movement are distributed throughout the nervous system. The brainstem is an important interface between upper motor centers involved in action planning and circuits in the spinal cord ultimately leading to execution of body movements. Here we focus on recent work using genetic and viral entry points to reveal the identity of functionally dedicated and frequently spatially intermingled brainstem populations essential for action diversification, a general principle conserved throughout evolution. Brainstem circuits with distinct organization and function control skilled forelimb behavior, orofacial movements, and locomotion. They convey regulatory parameters to motor output structures and collaborate in the construction of complex natural motor behaviors. Functionally tuned brainstem neurons for different actions serve as important integrators of synaptic inputs from upstream centers, including the basal ganglia and cortex, to regulate and modulate behavioral function in different contexts.
Keywords:
brainstem
motor control
neuronal cell types
skilled forelimb movement
orofacial behavior
locomotion
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
13.2
Papers:
930
Citations:
1.3W
Organization
Cited Papers
ShareSaveShareSaveA fluorescent chemosensor for Sn2+ and Cu2+ based on a carbazole-containing diarylethene.png)
RSC AdvancesOAAI
RSC AdvancesIF0
OAAIShareSave
ShareSave
View more