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Building basement membranes with computational approaches
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DOI：10.1016/j.matbio.2025.07.001.png)
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Abstract
En 中文
• Basement membrane (BM) components are described in several resources, but information about their interactions is lacking. • Systems biology approaches address the challenge of harnessing data by applying techniques such as network analysis and computational modelling. • We describe key elements of BM structure, composition and dynamics together with the application of computational modelling. • Once BM organising principles have been defined, disease models can be developed showing how the loss of specific BM components leads to dysfunction.
Keywords:
basement membrane
multi-omics
systems biology
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