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Calcium signalling - an overview

delete2001-02-01
delete477
PRE
AI
B
Bootman, MD *
C
Collins, TJ
C
Claire M. Peppiatt‐Wildman
L
Larissa S Prothero
L
Lauren J MacKenzie
P
Patrick De Smet
M
Marianne Travers
S
Stephen C. Tovey
J
Jeong Taeg Seo
M
Michael J. Berridge
F
Francesca Ciccolini
P
Peter Lipp
DOI：10.1006/scdb.2000.0211delete
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Abstract

Abstract

En 中文
Calcium (Ca2+) is an almost universal intracellular messenger controlling a diverse range of cellular processes, such as gene transcription (see Mellstrom and Naranjo, this issue), muscle contraction and cell proliferation. The ability of a simple ion such as Ca2+ to play a pivotal role in cell biology results from the facility that cells have to Ca2+ signals in the dimensions of space, time and shape Ca2+ signals. To generate the variety of observed Ca2+ signals, different cell types employ components selected from a Ca2+ signalling 'toolkit', which comprizes an array of signalling, homeostatic and sensory mechanisms. By mixing and marching components from the toolkit, cells can obtain Ca2+ signals that suit their physiology.
Keywords:
calcium
signalling
homeostasis
channel

Journal

Seminars in Cell and Developmental Biology cover
Seminars in Cell and Developmental Biology
IF:
6
Papers:
3.8K
Citations:
1.6W

Organization

No organization information available