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Calibration of a E -E telescope based on CeBr3 scintillator for secondary charged particles measurements in hadron therapy
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DOI：10.1088/1748-0221/21/01/P01037.png)
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Abstract
En 中文
Hadrontherapy is an established cancer treatment method that enables a more localized dose deposition compared to conventional radiotherapy, potentially reducing the dose to surrounding healthy tissues. However, a key limitation in current treatment planning lies in the limited experimental data available for the characterization of secondary particles generated by nuclear interactions of the primary beam with tissues, which directly impacts the accuracy of Monte Carlo tools and analytical models used in dose calculations. Indeed, this leads to the adoption of larger safety margins and can limit the use of hadrontherapy for treating certain complex or sensitive tumor locations. This work is part of the context of the characterization of secondary charged particles generated by ion beams in the energy range relevant for particle therapy applications, using a Delta E-E telescope comprising a CeBr3 crystal scintillator and a plastic scintillator. The calibration and response of this telescope to ions commonly used in clinical settings is presented in this work, highlighting adherence to Birks' law for accurate energy measurements. This study is the first to optimize a Delta E-E telescope combining CeBr3 and plastic scintillators specifically for secondary particle detection in hadrontherapy. It represents an essential step toward the experimental acquisition of nuclear data, enabling accurate measurement of secondary charged particles generated by therapeutic beams in tissue-equivalent materials. The system is designed for use in controlled experimental setups with energy ranges of interest for particle therapy that reproduce clinical conditions, with the goal of improving the predictive accuracy of treatment planning software through enhanced Monte Carlo simulation inputs. The system achieves an intrinsic energy resolution of about 10 MeV and a time resolution of 171-282 ps depending on the ion species and energy.
Keywords:
dE/dx detectors
Heavy-ion detectors
Instrumentation for hadron therapy
Instrumentation for particle-beam therapy
Journal
IF:
1.3
Papers:
528
Citations:
1.3W
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