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Can drug-induced platelet dysfunction be reversed?
10.1016/j.rpth.2025.103286
2025-12-09
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Abstract
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Antiplatelet drugs are used for treatment of arterial disease but side effects include an increased risk of bleeding. For patients with intracerebral haemorrhage, traumatic brain injury and lower gastrointestinal bleeding, mortality rates are higher for patients taking antiplatelet drugs. Reversing the effect of antiplatelet drugs may therefore reduce the risk of mortality and morbidity for these conditions. However, the benefits of any reversal agent must be balanced against the risk of thrombotic complications.
Keywords:
Antiplatelet drugs
platelet transfusion
tranexamic acid
desmopressin
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Journal
IF:
3.4
Papers: 1.9K
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Citations: 3.3K
Researchers
S
Suzanne Maynard
H-index:
0
Papers: 1
・
Citations: 0
A
Alexander P. Bye
H-index:
0
Papers: 1
・
Citations: 0
M
Michael Desborough
H-index:
25
Papers: 124
・
Citations: 2.7K
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U
university of oxford
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9.3W
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Citations: 58
U
University of Reading
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9.7K
Papers: 1.1W
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Citations: 1.7W
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