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Cannabinoid (CB) 1 receptor antagonists block fentanyl conditioned place preference but not fentanyl antinociception

delete2026-06-21
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PRE
AI
D
Devin Morrisson
E
Evan C. Smith
D
Dalal Alkhelb
T
Thanh Ho
L
Lipin Ji
A
Anna W. Sromek
A
Alexandros Makriyannis *
R
Rajeev I. Desai *
DOI：10.1016/j.drugalcdep.2026.113243delete
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Abstract

Abstract

En 中文
• CB1 neutral antagonists AM4113 and AM6527 block fentanyl-induced place preference • AM4113 and AM6527 do not interfere with the antinociceptive effects of fentanyl • CB1 neutral antagonists show therapeutic potential for opioid use disorder

Journal

Drug and Alcohol Dependence cover
Drug and Alcohol Dependence
IF:
3.6
Papers:
1.2W
Citations:
2.4W

Organization

N
northeastern university and mak scientific llc
Scholars:
9
Papers: 1
Citations: 0
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