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Catalyst-Free Synthesis of Symmetrical and Unsymmetrical Aminobenzophenones via Selective Nucleophilic Aromatic Substitution in Neat Amines
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DOI：10.1016/j.dyepig.2026.113838.png)
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Abstract
En 中文
• High-yielding, catalyst- and solvent- free SNAr affords a series of aminobenzophenones • The scalable, green protocol exhibits high atom economy and low E-factors • Selective mono-SNAr of difluorobenzophenones gives novel fluoro-aminobenzophenones • Sequential SNAr efficiently yields novel unsymmetrical bis(cyclic amino)benzophenones • High-yielding Suzuki-Miyaura coupling gives extended bi- and ter-phenyl derivatives
Keywords:
SNAr
aminobenzophenones
green chemistry
Suzuki-Miyaura coupling
selective substitution
Journal
IF:
4.2
Papers:
1.3W
Citations:
2.9W
Organization
No organization information available
Cited Papers