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CATH: comprehensive structural and functional annotations for genome sequences

delete2014-10-27
delete350
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OA
AI
I
Ian Sillitoe *
T
Tony E. Lewis
A
Alison Cuff
S
Sayoni Das
P
Paul Ashford
N
Natalie L. Dawson
N
Nicholas Furnham
R
Roman A. Laskowski
D
David Lee
J
Jonathan Lees
S
Sonja Lehtinen
R
Romain A. Studer
J
Janet M. Thornton
C
Christine Orengo
DOI:10.1093/nar/gku947delete
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Abstract

Abstract

En 中文
The latest version of the CATH-Gene3D protein structure classification database (4.0, http://www.cathdb.info) provides annotations for over 235 000 protein domain structures and includes 25 million domain predictions. This article provides an update on the major developments in the 2 years since the last publication in this journal including: significant improvements to the predictive power of our functional families (FunFams); the release of our 'current' putative domain assignments (CATH-B); a new, strictly non-redundant data set of CATH domains suitable for homology benchmarking experiments (CATH-40) and a number of improvements to the web pages.
Keywords:
PROTEIN
SUPERFAMILIES
PREDICTION
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Journal

Nucleic Acids Research cover
Nucleic Acids Research
IF:
13.1
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3.6W
Citations:
29.0W

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U
University College London
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B
Birkbeck University London
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U
university of london
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