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Cellular lipid imaging at the ultrastructural level
DOI:10.1016/j.tcb.2026.07.002.png)
Abstract
En 中文
Lipids are fundamental organizers of biological membranes, yet visualizing lipid species within subcellular organelles has remained beyond experimental reach. Lennartz et al. introduce Lipid-correlative light and electron microscopy (CLEM), a CLEM workflow that maps lipid species onto membrane ultrastructure with nanoscale precision, uncovering active sphingomyelin sorting within the early endosome.
Journal
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18.1
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3.1K
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