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Changes in Muscle Mass and Quality Mediate the Effect of High-Calorie Intake on Clinical Outcomes
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DOI:10.1002/jcsm.70355.png)
Abstract
En 中文
Critically ill patients frequently experienced acquired muscle dysfunction, which adversely affects outcomes. The relationship between calorie intake, muscle dysfunction and outcomes remains unclear. This study aims to determine if early calorie intake affects patients' outcomes through changes in skeletal muscle mass or quality, and to explore changes in muscle structure and underlying molecular pathways using limb muscle biopsies in a piglet model.
Keywords:
critical illness
elastography
nutrition
outcomes
skeletal muscle
ultrasound
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