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Changes of Clinical Practice Patterns of Allergen Immunotherapy in Korea

delete2025-01-01
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OA
AI
H
Hwa Young Lee
S
Sung‐Yoon Kang
K
Kyunghoon Kim
J
Ju Hee Kim
G
Gwanghui Ryu
J
Jin‐Young Min
K
Kyung Hee Park
S
So‐Young Park
M
Myong Soon Sung
Y
Young‐Soo Lee
E
Eun Ae Yang
H
Hye Mi Jee
E
Eun Kyo Ha
Y
Yoo Seob Shin
Y
Yong Won Lee
E
Eun Hee Chung
S
Sun Hee Choi
Y
Young‐Il Koh
S
Seon-Tae Kim
D
Dong‐Ho Nahm
J
Jung‐Won Park
J
Jung Yeon Shim
D
Doo Hee Han
M
Man Yong Han
S
Sang Min Lee
J
Jeong‐Hee Choi
DOI:10.4168/aair.2025.17.2.271delete
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Abstract

Abstract

En 中文
This study aimed to identify recent changes ofAIT treatment behaviors in real-world clinical practice using a questionnaire survey in Korea. The questionnaire on AIT prescriptions and practical experiences was distributed to all members of the Korean Academy ofAsthma Allergy and Clinical Immunology in June 2022. The responses were analyzed and compared with the results from 2009 and 2017. In total, 115 responses (10.1%) were collected; 58 (50.4%) from internal medicine, 34 (29.6%) from pediatricians, and 21 (18.3%) from otolaryngologists. The prescription rate for subcutaneous immunotherapy (SCIT) was 53.8%, showing a decrease from those in 2009 and 2017; however, that for sublingual immunotherapy (SLIT) increased steadily, reaching 17.9% in 2009, 40.3% in 2017, and 46.2% in 2022. The prescription rates for asthma and atopic dermatitis increased by 4.6% and 7.9%, respectively. The most frequently prescribed allergens for SCIT in 2022 were house dust mites (32.9%), pollen (30.6%), and animal dander (28.2%), with the rate for animal dander showing a significant increase from 10.3% in 2009. Most physicians (93%) used mixed allergens for SCIT, with 42.8% using a combination of 5 or more allergens. Fifty-eight (67.4%) respondents reported cases of anaphylaxis during SCIT and 36.2% reported systemic adverse reactions during SLIT. In conclusion, SLIT prescriptions, AIT for asthma and atopic dermatitis, and AIT with animal dander increased significantly from 2009 to 2022. Serial surveys of AIT practices are helpful in identifying the changes of real-world clinical practice of AIT.
Keywords:
Allergens
immunotherapy
surveys and questionnaires
asthma
atopic dermatitis
allergic rhinitis

Journal

A
Allergy Asthma and Immunology Research
IF:
4.3
Papers:
1.1K
Citations:
2.7K

Organization

S
Soon Chun Hyang Univ
Scholars:
4
Papers: 5
Citations: 3
C
Chung Ang University
Scholars:
1.3W
Papers: 1.4W
Citations: 133
C
CHA Univ
Scholars:
209
Papers: 118
Citations: 40
S
Seoul Natl Univ
Scholars:
4.1K
Papers: 1.9K
Citations: 590
K
Kyung Hee Univ Hosp Gangdong
Scholars:
16
Papers: 14
Citations: 2
C
Chungnam Natl Univ
Scholars:
1.0K
Papers: 482
Citations: 112
C
Chonnam Natl Univ
Scholars:
918
Papers: 481
Citations: 122
C
Catholic Univ Korea
Scholars:
905
Papers: 449
Citations: 101
S
Sungkyunkwan Univ
Scholars:
2.2K
Papers: 1.1K
Citations: 343
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