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Characterization of response-adapted surgery following neoadjuvant systemic therapy in oral cavity cancer

delete2026-06-30
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PRE
AI
R
R. Lu
L
Lara Dunn
K
Kenric Tam
M
Michael T. Starc
R
Richard J. Wong
I
Ian Ganly
S
Snehal G. Patel
N
Nancy Lee
W
Winston Wong
M
Marc A. Cohen
A
Alan L. Ho
J
Jennifer R. Cracchiolo *
DOI：10.1016/j.oraloncology.2026.108060delete
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Abstract

Abstract

En 中文
• NST reduced surgical burden in 63 % of patients with locally advanced OCSCC. • Surgical de-escalation was strongly associated with pathologic response. • Negative margins were maintained in 97 % of de-escalated cases. • Reduced resection and reconstruction were the main drivers of de-escalation. • Surgical burden should be considered as an endpoint for neoadjuvant oral cancer trials.

Journal

Oral Oncology cover
Oral Oncology
IF:
3.9
Papers:
9.0K
Citations:
1.4W

Organization

M
memorial sloan kettering cancer center
Scholars:
2.3K
Papers: 660
Citations: 1
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