.png){kind=icon}
.png){kind=icon}
Return
Chemokine receptor CCR1 restrains adipose tissue remodelling via cAMP/PKA/CREB signalling and adipocyte‒macrophage crosstalk in mice
.png){kind=icon}
OA
AI
S
M
Y
M
X
Y
M
Y
Y
L
DOI：10.1002/ctm2.70762.png)
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
Adipose tissue remodelling, encompassing white adipose tissue (WAT) browning alongside brown adipose tissue (BAT) activation, holds promise for combating obesity, yet the endogenous chemokine receptors that restrain this plasticity remain ill-defined. Here, we uncover that C‒C chemokine receptor 1 (CCR1) restrains adipocyte remodelling and energy expenditure.
Keywords:
adipose remodelling
cAMP/PKA/CREB pathway
C‒C chemokine receptor 1
energy expenditure
insulin resistance
obesity
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
6.8
Papers:
2.6K
Citations:
9.6K
Organization
Cited Papers