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CHIP protects rheumatoid arthritis progression by targeting TRAF6 in arthritis animal models
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DOI：10.1016/j.jot.2026.101175.png)
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Abstract
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Carboxyl terminus of HSC70-interacting protein (CHIP) serves as a quality control protein that involves in inflammation and immunity, bone remodeling and tumorigenesis. However, the role of CHIP in joint disease such as rheumatoid arthritis (RA) is less explored.
Keywords:
Carboxyl terminus of HSC70-Interacting protein
Collagen-induced arthritis
Fibroblast-like synoviocytes
Joint inflammation
Rheumatoid arthritis
TNF receptor associated factor 6
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