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Cholesterol and related sterols differentially modulate lipid domain dynamics in model membranes: A dual-probe analysis of domain-specific effects
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DOI：10.1016/j.chemphyslip.2025.105550.png)
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Abstract
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• Laurdan and Cholesterol-pyrene reveal different behavior of membrane bilayer. • Lipid order and mobility are not simply correlated depending on molecular spaces. • The ordering effect of sterols is different in phosphatidylcholine and sphingomyelin. • In sphingomyelin, hydroxysterols show strong Lo character near the head-groups. • In sphingomyelin, hydroxysterols show low Lo character near the membrane center.
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