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Cingulate cortex: Diverging data from humans and monkeys

delete2009-11-01
delete101
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OA
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M
Michael W. Cole *
N
Nick Yeung
W
Winrich A. Freiwald
M
Matthew Botvinick
DOI:10.1016/j.tins.2009.07.001delete
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Abstract

Abstract

En 中文
Cognitive neuroscience research relies, in part, on homologies between the brains of human and non-human primates. A quandary therefore arises when presumed anatomical homologues exhibit different functional properties. Such a situation has recently arisen in the case of the anterior cingulate cortex (ACC). In humans, numerous studies suggest a role for ACC in detecting conflicts in information processing. Studies of macaque monkey ACC, in contrast, have failed to find conflict-related responses. We consider several interpretations of this discrepancy, including differences in research methodology and cross-species differences in functional neuroanatomy. New directions for future research are outlined, emphasizing the importance of distinguishing illusory cross-species differences from the true evolutionary differences that make our species unique.
Keywords:
MEDIAL FRONTAL-CORTEX
RESPONSE-CONFLICT
COGNITIVE CONTROL
CONTROL NETWORK
ERROR-DETECTION
ANTERIOR
PERFORMANCE
ARCHITECTURE
NEURONS
FMRI
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Journal

Trends in Neurosciences cover
Trends in Neurosciences
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15.1
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5.3K
Citations:
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rockefeller university
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