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Clinical outcomes following switch from risankizumab to guselkumab in Crohn’s disease: a real-world case series

delete2026-06-25
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OA
AI
A
Amar Farkouh
N
Nabil Nathoo-Khedri
A
Alice Dufresne
H
Homa Danaie
R
Robert Battat *
DOI:10.1093/ecco-jcc/jjag089delete
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Abstract

Abstract

En 中文
Risankizumab is an interleukin (IL)-23 inhibitor that is effective for the treatment of moderate-to-severe Crohn’s disease (CD). However, many patients experience loss of response. Switching within the IL-23 inhibitor class to agents with more frequent dosing, such as guselkumab, may represent a salvage strategy, though no supporting data exist. We aimed to describe outcomes following switching between IL-23 antagonists.

Journal

Journal of Crohn's and Colitis cover
Journal of Crohn's and Colitis
IF:
8.7
Papers:
7.5K
Citations:
1.6W

Organization

U
university of montreal
Scholars:
839
Papers: 431
Citations: 1