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Clot contraction of whole blood diminishes during storage and can be restored by adding platelets

delete2026-07-06
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PRE
AI
H
Halen Turner
M
Monica Seadler
Y
Youjie Zhang
M
Matteo Ferraresso
C
Christian J. Kastrup *
DOI:10.1111/trf.70322delete
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Abstract

Abstract

En 中文
The contraction of blood clots is a dramatic platelet-dependent process that minimizes the impact of thrombosis and supports the closure of lacerations. Whole blood (WB) stored up to 35 days is increasingly used to treat hemorrhagic shock, but the clot contractibility of this stored blood is unknown. We hypothesized that clot contractibility decreases during storage but can be restored by adding platelets.
Keywords:
apheresis platelets
clot retraction
hemostasis
polyhedrocytes
transfusion

Journal

Transfusion cover
Transfusion
IF:
2
Papers:
718
Citations:
1.3W

Organization

V
versiti blood research institute
Scholars:
134
Papers: 43
Citations: 0
M
medical college of wisconsin
Scholars:
1.7W
Papers: 1.2W
Citations: 9
U
University of British Columbia
Scholars:
6.8W
Papers: 6.1W
Citations: 8.6W
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