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Coenzyme A-Regulated Competitive Coordination-Driven Luminescence for Portable In-Cell Detection of Histone Acetyltransferase Activity
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DOI:10.1016/j.snb.2026.140667.png)
Abstract
En 中文
• A coordination-regulated Eu3+-Au NCs platform enables sensitive Tip60 detection. • DPA enhances luminescence via efficient antenna-mediated energy transfer. • CoA induces competitive coordination, leading to reversible signal quenching. • A smartphone-based system allows portable and real-time activity readout. • The platform reveals dynamic Tip60 regulation during cellular pyroptosis.
Journal
IF:
7.7
Papers:
3.3W
Citations:
12.6W
