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Coexistence of Domains Composed of Intercellular Lipids in Stratum Corneum as Studied by X-Ray Diffraction and Differential Scanning Calorimetry
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DOI：10.1016/j.chemphyslip.2025.105552.png)
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Abstract
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• In stratum corneum, intercellular lipids form domains, and a domain should be constructed by one lamellar structure and one hydrocarbon-chain packing structure. • To solve the structural formation in a domain, differential scanning calorimetry and X-ray diffraction experiments as a function of temperature were performed. • Importantly, the short-period lamellar structure and the original orthorhombic hydrocarbon-chain packing structure are in the same domain, then the structures within this domain play a role in regulating the water content in stratum corneum.
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