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Cognitive Processes and Neurophysiological Mechanisms of Time Processing in Parkinson’s Disease: A Narrative Review
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DOI：10.1016/j.neubiorev.2026.106719.png)
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Abstract
En 中文
• Time processing is impaired in PD and contribute to the motor and cognitive manifestations of the disease. • Time processing deficits involve dysfunction of basal ganglia, cerebellar, and prefrontal circuits. • Dopaminergic therapy improves motor but not all cognitive timing functions. • Non-dopaminergic systems also contribute to timing deficits in PD.
Keywords:
Parkinson’s disease
time processing
dopamine
basal ganglia
cognitive impairment
bradyphrenia
bradykinesia
working memory
attention
dopaminergic therapy
timing tasks
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