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Combined effects of diet and genetic predisposition on kidney function outcomes
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DOI：10.1093/ckj/sfag196.png)
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Abstract
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Chronic kidney disease (CKD) is a significant global health concern. While diet is crucial to CKD prevention and management, the interaction between diet and genetic predisposition to CKD is underexplored. We conducted an exploratory investigation of the interplay between a polygenic score (PGS) for kidney function and dietary exposures in relation to glomerular filtration rate estimated based on serum creatinine (eGFRcrea) on 5717 generally healthy adult participants of the Cooperative Health Research In South Tyrol (CHRIS) study.
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