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Comparative analysis of patient-derived organoids and patient-derived xenografts as avatar models for predicting response to anti-cancer therapy
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DOI：10.1016/j.ctrv.2026.103190.png)
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Abstract
En 中文
• This is the first systematic comparison of PDX and PDO models using matched patient- response data. • PDX and PDO show comparable accuracy in predicting matched-patient treatment response. • Response in PDOs is associated with prolonged progression-free survival in matched patients.
Keywords:
PDX
PDO
organoid
xenograft
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