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Comparative risk of ventricular arrhythmia and sudden cardiac death among acetylcholinesterase inhibitors in dementia: A population-based cohort study

delete2026-07-02
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PRE
AI
H
Hsi-Yu Lai
L
Lin-Chieh Meng
Y
Yi-Jia Ye
H
Ho-Min Chen
L
Liang-Kung Chen *
F
Fei‐Yuan Hsiao *
DOI:10.1002/bcp.70656delete
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Abstract

Abstract

En 中文
Previous studies have suggested that acetylcholinesterase inhibitors (AChEIs) may be associated with an increased risk of ventricular arrhythmia or sudden cardiac death, potentially related to QTc prolongation. However, evidence comparing the real-world risk of severe cardiac conduction outcomes among the three AChEIs—donepezil, galantamine and rivastigmine—remains limited.
Keywords:
acetylcholinesterase inhibitor
Alzheimer's disease
dementia
sudden cardiac death
ventricular arrhythmia

Journal

British Journal of Clinical Pharmacology cover
British Journal of Clinical Pharmacology
IF:
3
Papers:
8.5K
Citations:
1.8W

Organization

T
taipei veterans general hospital
Scholars:
883
Papers: 346
Citations: 0
N
national taiwan university
Scholars:
5.8K
Papers: 2.3K
Citations: 0
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