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Comparative study for managing OCD and anxiety symptoms (COSMOS) study: Rationale, design, and methods

delete2026-03-01
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PRE
AI
J
Joanna X. Zhou
O
Ogechi Cynthia Onyeka
J
Jeffrey A. Carter
A
Annika Myers
A
Adam Garcia
C
Contreras-Munoz, Janie
M
Marianna Messerli
B
Brian Dang
A
Alyssa Vieira
A
Ahmed, Annisa
A
Ayton, Daphne M.
B
Boedeker, Peter
A
Andrew G. Guzick
T
Ticiane Silva
H
Hannah C. Moore
E
Erika S. Trent
C
Candelari, Abigail E.
A
Amanda D. Palo
E
Eric A. Storch *
DOI:10.1016/j.cct.2026.108286delete
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Abstract

Abstract

En 中文
Anxiety and obsessive-compulsive disorders are common among children and adolescents and, if left untreated, can lead to further psychiatric morbidity and impairment. Practical barriers, such as financial constraints, limited availability of therapists, and time limitations of families, may impede access to evidence-based treatments. Low-intensity treatments show promise in addressing these barriers while conserving resources for those who require additional support. However, further empirical evidence is needed regarding the comparative efficacy of different interventions. To address this gap, we detail the protocol for a randomized controlled trial that compares the effectiveness of three different low-intensity therapy interventions-internet guided cognitive-behavioral therapy, parent-led treatment, and relaxation therapy-and explores the underlying mechanisms of each.
Keywords:
Anxiety
Obsessive-compulsive disorder
Youth
Cognitive-behavioral therapy
Low-intensity treatment
Parent-led

Journal

Contemporary Clinical Trials cover
Contemporary Clinical Trials
IF:
1.9
Papers:
197
Citations:
5.7K

Organization

B
baylor college of medicine
Scholars:
3.7K
Papers: 1.4K
Citations: 0
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