Comparison of dual-energy iodine and standard subtraction methods for myocardial extracellular volume quantification using cardiac computed tomography

doi:10.1016/j.jcct.2025.03.009

Comparison of dual-energy iodine and standard subtraction methods for myocardial extracellular volume quantification using cardiac computed tomography

2025-04-08

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PRE

AI

Felipe Contreras Yametti

A

Andrea Scotti

W

Winsome Elliott-Bailey

DOI：10.1016/j.jcct.2025.03.009

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Abstract

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Computed tomography (CT)-derived extracellular volume fraction (ECV) quantifies myocardial fibrosis noninvasively, comparable to cardiovascular magnetic resonance. The conventional subtraction method (ECV-conv) requires dedicated pre- and post-contrast acquisitions, while the dual-energy spectral method (ECV-spec) uses only the post-contrast phase. We aimed to compare these methods in patients undergoing CT planning for transcatheter aortic valve replacement (TAVR).

Keywords:

ECV

CT

myocardial fibrosis

TAVR

dual-energy spectral imaging

Comparison of dual-energy iodine and standard subtraction methods for myocardial extracellular volume quantification using cardiac computed tomography

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