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Complementing CD20 antibodies' effector functions
DOI:10.1182/blood.2024027767.png)
Abstract
En 中文
In this issue of Blood, Baskar et al describe an innovative approach to enhance CD20 antibody efficacy by employing their complement-activating capacity to deposit C3d as neoantigen for novel antibodies in xenografted mouse models.1
Journal
IF:
23.1
Papers:
5.6K
Citations:
16.6W
Organization
Cited Papers
Unlocking the Power of Complement-Dependent Cytotoxicity: Engineering Strategies for the Development of Potent Therapeutic Antibodies for Cancer Treatments
BIODRUGS
IF6.9
Daratumumab in pediatric relapsed/refractory acute lymphoblastic leukemia or lymphoblastic lymphoma: the DELPHINUS study
Blood
IF0
An anti-C3b(i) mAb enhances complement activation, C3b(i) deposition, and killing of CD20+ cells by rituximab
Blood
IF0
no more

