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Complosome as a key modulator of cellular senescence, aging and age-related diseases
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DOI：10.1016/j.arr.2026.103274.png)
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Abstract
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• Intracellular C3 (intC3) crosstalks with the mTOR, NF-κB, and AMPK pathways. • IntC3 plays cell- and tissue-specific roles across tissues. • Complosome bridges aging hallmarks with age-related disease. • Complosome is a therapeutic target for aging and age-related diseases.
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