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Congenital Ichthyosis is Associated with Increased Risk of Allergic Disorders

delete2026-08-06
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PRE
AI
M
Mara B. O’Connor
R
Riddhi Patel
H
Hannah Soltani
Z
Ziyou Ren
A
Amy S. Paller *
DOI:10.1016/j.jaci.2026.07.016delete
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Abstract

Abstract

En 中文
The congenital ichthyoses are rare, hereditary epidermal differentiation disorders with severely impaired skin barrier function. Patients with atopic dermatitis and one form of congenital ichthyosis, Netherton syndrome, are known to have an increased risk of atopy, presumably linked to barrier impairment. However, an increased risk of atopy has not been assessed in individuals with other congenital ichthyoses, despite their severe barrier impairment.

Journal

Journal of Allergy and Clinical Immunology cover
Journal of Allergy and Clinical Immunology
IF:
11.2
Papers:
3.7W
Citations:
5.6W

Organization

N
Northwestern University
Scholars:
6.1W
Papers: 5.2W
Citations: 3.9K
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