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Contrast-enhanced mammography in the setting of neoadjuvant therapy from a multidisciplinary perspective
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DOI：10.1186/s13244-026-02294-5.png)
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Abstract
En 中文
Contrast-enhanced mammography (CEM) is a morphofunctional imaging technique that is gaining interest and acceptance in clinical practice. With increasing use of neoadjuvant therapy (NAT) in breast cancer and of precision medicine, the need for equitable access to appropriate high-quality advanced imaging for monitoring response has become ever more relevant. CEM is an imaging alternative for NAT monitoring, with encouraging initial results and a good logistical profile. In this educational review from a practical perspective, we explore key aspects for response assessment of NAT and CEM roles in this setting, based on relevant literature and the authors’ clinical experience. Pearls and pitfalls, as well as opportunities and challenges for NAT monitoring with CEM, will be approached from the perspectives of the radiologist, the oncologist, the surgeon, the pathologist, and the patient. The early experience with CEM in the NAT setting is positive, encouraging its further development, not only from the radiologist's view but also from a broad multidisciplinary perspective.
Keywords:
Breast cancer
Contrast-enhanced mammography
Neoadjuvant therapy
Precision medicine
Pathology
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