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Converging engineered models of cancer and artificial intelligence
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DOI：10.1038/s41568-026-00966-4.png)
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Abstract
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No existing model can reliably predict how an individual cancer will evolve. The future of precision oncology lies not in increasingly sophisticated in vitro tumour models or in artificial intelligence alone, but in the iterative feedback loop between the two. No existing model can reliably predict how an individual cancer will evolve. In this Comment, Guimarães and Reis argue that the future of precision oncology lies not in increasingly sophisticated in vitro tumour models or in artificial intelligence alone, but in the iterative feedback loop between the two.
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