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Coupling synthetic negative feedback loops
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DOI：10.1016/j.chempr.2025.102692.png)
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Abstract
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• The threshold of a synthetic NFL can be tuned through kinetic/thermodynamic control • The coupling of NFLs with different thresholds results in hierarchical responses • NFLs competing over the same resource result in emergent systems properties
Keywords:
synthetic NFL
kinetic control
thermodynamic control
hierarchical responses
emergent properties