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CPGPrompt: translating clinical guidelines into large language model-executable decision support

delete2026-02-26
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PRE
AI
R
Ruiqi Deng, MS
G
Geoffrey Martin, MA
T
Tony Wang, MS
G
Gongbo Zhang
Y
Yi Liu
C
Chunhua Weng
Y
Yanshan Wang
J
Justin Rousseau
Y
Yifan Peng *
DOI:10.1093/jamia/ocag026delete
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Abstract

Abstract

En 中文
Clinical practice guidelines (CPGs) provide evidence-based recommendations for patient care; however, integrating them into artificial intelligence (AI) remains challenging. Previous approaches, such as rule-based systems or black-box AI models, face significant limitations, including poor interpretability, inconsistent adherence to guidelines, and narrow domain applicability. To address this, we develop and validate CPGPrompt, an auto-prompting system that converts narrative clinical guidelines into large language models (LLMs).
Keywords:
Clinical Practice Guidelines
Large Language Models
Decision Support
Auto-prompting
Artificial Intelligence

Journal

Journal of the American Medical Informatics Association cover
Journal of the American Medical Informatics Association
IF:
4.6
Papers:
417
Citations:
1.6W

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columbia university
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