1
Return

Cross-Platform Comparative Spatial Transcriptomics in High-Grade Serous Carcinoma

delete2026-05-15
delete0
delete
OA
AI
O
Omar Youssef *
L
Lars Selander
S
Shuyu Zheng
L
Lilla Csellar
S
Satu Hänninen
J
Jing Tang
O
Olli Carpén
A
Anna Laury
DOI:10.1016/j.labinv.2026.106134delete
deleteOriginal
deleteShare
deleteSave
View PDF
Abstract

Abstract

En 中文
High-grade serous carcinoma (HGSC) is a remarkably heterogeneous tumor. The purpose of this study was to directly compare the reproducibility of transcriptomic profiles and biologically relevant molecular features across two spatial transcriptomics platforms—GeoMx Digital Spatial Profiler (GeoMx) and Visium Spatial Gene Expression (Visium) using AI-defined tumor regions associated with clinical outcome.
Keywords:
High grade serous tubo-ovarian carcinoma
HGSC
GeoMx
Visium
spatial transcriptomics
ovarian cancer
RNA-ISH
AI Summary

AI Summary

Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

Laboratory Investigation cover
Laboratory Investigation
IF:
4.2
Papers:
5.4K
Citations:
1.1W

Organization

U
University of Helsinki
Scholars:
4.2K
Papers: 1.7K
Citations: 5.1W
K
Karolinska Institute
Scholars:
737
Papers: 378
Citations: 2
Cited Papers

Cited Papers

Citing Papers

Citing Papers