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Crystal Shape Engineering
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DOI：10.1021/ie800900f.png)
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Abstract
En 中文
In an industrial crystallization process, crystal shape strongly influences end-product quality and functionality, as well as downstream processing. In addition, nucleation events, solvent effects, and polymorph selection play critical roles in both the design and operation of a crystallization plant and the patentability of the product and process. Therefore, investigation of these issues, with respect to a priori prediction, is (and will continue to be) an important avenue of research. In this review, we discuss the state-of-the-art in modeling crystallization processes over a range of length scales relevant to nucleation through process design. We also identify opportunities for continued research and specific areas where significant advancements are needed.
Keywords:
ATOMIC-FORCE MICROSCOPY
POPULATION BALANCE-EQUATIONS
L-GLUTAMIC ACID
MULTIDIMENSIONAL CRYSTALLIZATION PROCESSES
INDUSTRIAL BATCH CRYSTALLIZATION
TAILOR-MADE ADDITIVES
IN-SITU
IMAGE-ANALYSIS
POLYMORPHIC TRANSFORMATION
GROWTH-KINETICS
Journal
I
IF:
3.9
Papers:
4.0W
Citations:
9.6W
Organization
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