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CTV-MIND: A cortical thickness-volume integrated individualized morphological network model to explore disease progression in temporal lobe epilepsy

delete2025-07-09
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OA
AI
X
Xinyan Liu
J
Jiaqi Han
X
Xiating Zhang
B
Boxuan Wei
L
Lu Xu
Q
Qi‐Lin Zhou
王玉平 (Yuping Wang) *
Y
Yicong Lin *
J
Jicong Zhang *
DOI:10.1016/j.nicl.2025.103843delete
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Abstract

Abstract

En 中文
• Novel MRI-based CTV-MIND framework reveals duration-related hub reorganization in TLE. • Reorganized hubs drive disease duration-dependent premature brain aging. • Network node alterations significantly correlate with cortical atrophy in TLE.
Keywords:
Brain network reorganization
Brain age prediction
CTV-MIND
MRI
TLE
MIND
Morphometric INverse Divergence
CT
cortical thickness
Vol
gray matter volume
CTV-MIND
Cortical Thickness-Volume Integrated MIND
TLE
Temporal lobe epilepsy
HC
healthy controls
MRI
magnetic resonance imaging
KL
Kullback-Leibler
Dc
node degree centrality
Ne
node efficiency
NBS
network-based statistics
FDR
false discovery rate
ANCOVA
analysis of covariance
AI Summary

AI Summary

Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

NeuroImage-Clinical cover
NeuroImage-Clinical
IF:
3.6
Papers:
3.9K
Citations:
1.5W

Organization

C
Capital Medical University
Scholars:
5.3W
Papers: 3.3W
Citations: 3.2W
B
Beihang University
Scholars:
5.0W
Papers: 4.0W
Citations: 37