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Current perspectives on RNAi-based biopesticides in the green management of insect pests: advances, challenges, and future directions
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DOI：10.1016/j.biocontrol.2026.106041.png)
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Abstract
En 中文
• Coleopteran vs. lepidopteran RNAi disparities linked to SID-1 polymorphism and dsRNase evolution. • Microbial dsRNA vs regulatory fragmentation (EPA/EFSA) limits access. • Nano-encapsulation extends dsRNA half-life overcoming instability barriers for topical dsRNA. • RNAi-Bt combos delay but dsRNase/SID-1 adaptations risk sustainability. • CRISPR + pheromone delivery for ecology-sensitive smallholder solutions.
Keywords:
RNA interference (RNAi)
Pest management
Transgenic crops
dsRNA delivery
Sustainable agriculture
Bt resistance
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