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Cyanobacterial biological processes: A physics-informed neural network approach to biochemical kinetics
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DOI：10.1016/j.cherd.2026.06.055.png)
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Abstract
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• PINNs integrated biochemical kinetics into fed-batch bioreactor modeling. • PPO optimized nitrate-feeding strategies for enhanced C-PC production. • PINN improved extrapolation under sparse experimental datasets. • PPO-guided optimization improved predicted C-PC yield by up to 73%. • Physics-informed learning preserved biologically consistent predictions.
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