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Decellularized dermal scaffold biofunctionalized with quercetin nanoparticles enhances angiogenesis and attenuates inflammation in type 2 diabetic wounds
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DOI：10.1016/j.tice.2026.103562.png)
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Abstract
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• Quercetin-functionalized dermal scaffold accelerates diabetic wound healing. • Bioengineered scaffold enhances angiogenesis in type 2 diabetic wounds. • Treatment reduces inflammation and improves regenerative remodeling. • Antioxidant defense increased (GSH, SOD, CAT) while MDA decreased. • Scaffold improves collagen density and biomechanical strength.
Keywords:
Quercetin
Dermal scaffold
Angiogenesis
Diabetic wounds
Inflammation
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