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Decoding neuronal networks: A Reservoir Computing approach for predicting connectivity and functionality
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DOI：10.1016/j.neunet.2024.107058.png)
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Abstract
En 中文
In this study, we address the challenge of analyzing electrophysiological measurements in neuronal networks. Our computational model, based on the Reservoir Computing Network (RCN) architecture, deciphers spatiotemporal data obtained from electrophysiological measurements of neuronal cultures. By reconstructing the network structure on a macroscopic scale, we reveal the connectivity between neuronal units. Notably, our model outperforms common methods such as Cross-Correlation, Transfer-Entropy, and a recently developed related algorithm in predicting the network's connectivity map. Furthermore, we experimentally validate its ability to forecast network responses to specific inputs, including localized optogenetic stimuli.
Keywords:
Neural models
Reservoir computing
Electrophysiological data
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