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Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression
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DOI：10.1002/1873-3468.70402.png)
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Abstract
En 中文
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three-dimensional cancer models more accurately reflects in vivo conditions compared to conventional two-dimensional systems. Matrix engineering through bioscaffolds supports physiologically relevant tumor modeling, while matrix-based platforms offer valuable tools for preclinical research and therapeutic development.
Keywords:
(matrix-based) bioscaffolds
3D culture platforms
cancer
extracellular matrix
tumor traps
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