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Decrease in fMRI brain activation during working memory performed after sleeping under 10 lux light
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DOI：10.1038/srep36731.png)
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Abstract
En 中文
The aim of this study was to investigate the effect of exposure to dim light at night (dLAN) when sleeping on functional brain activation during a working-memory tasks. We conducted the brain functional magnetic resonance imaging (fMRI) analysis on 20 healthy male subjects. All participants slept in a polysomnography laboratory without light exposure on the first and second nights and under a dim-light condition of either 5 or 10 lux on the third night. The fMRI scanning was conducted during n-back tasks after second and third nights. Statistical parametric maps revealed less activation in the right inferior frontal gyrus (IFG) after exposure to 10-lux light. The brain activity in the right and left IFG areas decreased more during the 2-back task than during the 1- or 0-back task in the 10-lux group. The exposure to 5-lux light had no significant effect on brain activities. The exposure to dLAN might influence the brain function which is related to the cognition.
Keywords:
EXPOSURE
RESPONSES
DEPRIVATION
MELATONIN
NIGHT
HUMANS
TASK
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Decreased brain activation during a working memory task at rested baseline is associated with vulnerability to sleep deprivation.png)
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CURRENT BIOLOGYIF7.5
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