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Deep brain stimulation: A narrative review of its applicability for major depressive disorder
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DOI：10.1016/j.pnpbp.2026.111721.png)
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Abstract
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• Deep brain stimulation is a promising option for resistant depression. • DBS targets mood-related circuits such as SCC, NAcc, and VC/VS. • Evidence is promising but limited by small samples and study heterogeneity.
Keywords:
Deep brain stimulation
Treatment-resistant depression
Major depressive disorder
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