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Deep Convolutional Neural Network-Based Computer-Aided Detection System for COVID-19 Using Multiple Lung Scans: Design and Implementation Study

delete2021-04-26
delete59
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OA
AI
M
Mustafa Ghaderzadeh
F
Farkhondeh Asadi *
R
Ramezan Jafari
D
Davood Bashash
H
Hassan Abolghasemi
M
Mehrad Aria
DOI:10.2196/27468delete
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Abstract

Abstract

En 中文
Background: Owing to the COVID-19 pandemic and the imminent collapse of health care systems following the exhaustion of financial, hospital, and medicinal resources, the World Health Organization changed the alert level of the COVID-19 pandemic from high to very high. Meanwhile, more cost-effective and precise COVID-19 detection methods are being preferred worldwide. Objective: Machine vision-based COVID-19 detection methods, especially deep learning as a diagnostic method in the early stages of the pandemic, have been assigned great importance during the pandemic. This study aimed to design a highly efficient computer-aided detection (CAD) system for COVID-19 by using a neural search architecture network (NASNet)-based algorithm. Methods: NASNet, a state-of-the-art pretrained convolutional neural network for image feature extraction, was adopted to identify patients with COVID-19 in their early stages of the disease. A local data set, comprising 10,153 computed tomography scans of 190 patients with and 59 without COVID-19 was used. Results: After fitting on the training data set, hyperparameter tuning, and topological alterations of the classifier block, the proposed NASNet-based model was evaluated on the test data set and yielded remarkable results. The proposed model's performance achieved a detection sensitivity, specificity, and accuracy of 0.999, 0.986, and 0.996, respectively. Conclusions: The proposed model achieved acceptable results in the categorization of 2 data classes. Therefore, a CAD system was designed on the basis of this model for COVID-19 detection using multiple lung computed tomography scans. The system differentiated all COVID-19 cases from non-COVID-19 ones without any error in the application phase. Overall, the proposed deep learning-based CAD system can greatly help radiologists detect COVID-19 in its early stages. During the COVID-19 pandemic, the use of a CAD system as a screening tool would accelerate disease detection and prevent the loss of health care resources.
Keywords:
artificial intelligence
classification
computer-aided detection
computed tomography scan
convolutional neural network
coronavirus
COVID-19
deep learning
machine learning
machine vision
model
pandemic

Journal

Journal of Medical Internet Research cover
Journal of Medical Internet Research
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6
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9.7K
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5.0W

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baqiyatallah university of medical sciences (bmsu)
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Shahid Beheshti University Medical Sciences
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Shiraz University
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