Defining Rapid Early Progression in Glioblastoma — A Volumetric Approach

2026-06-08

Vikram Munlapudi, BS

Jacob Guzzino, BS

David J Crompton, MD

Shubhi Agarwal, MD

Eric J Lehrer, MD

Shelby Kern, PA-C, MS

Aaron Bogan, MA

Sujay A Vora, MD

Alfredo Quinones-Hinojosa, MD

Terry C Burns, MD, PhD

Wendy J Sherman, MD

Paul D Brown, MD

Nadia Laack, MD

Jennifer Peterson, MD

Joon H Uhm, MD

Michael W Ruff, MD

Ugur T Sener, MD

William G Breen, MD

Daniel M Trifiletti, MD *

DOI：10.1093/noajnl/vdag153

Original

Original request for help

Save

Abstract

En 中文

The current treatment of glioblastoma involves resection followed by radiotherapy (RT) and temozolomide. Rapid early progression (REP) of tumor in the surgery-to-radiotherapy interval (SRI) has been described using categorical or semi-quantitative assessments and is associated with inferior clinical outcomes. This study seeks to establish and validate a quantitative definition for REP and examine how REP could inform future therapy.

Defining Rapid Early Progression in Glioblastoma — A Volumetric Approach

Abstract

Journal

Organization

Cited Papers

Citing Papers