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Deletion of RalGAPβ protects pancreatic β cells and improves glycemic control
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王
DOI：10.1111/dom.70133.png)
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Abstract
En 中文
Pancreatic β cell homeostasis involving their proliferation, growth, and apoptosis is critical for postprandial insulin levels and glycaemic control. The regulatory mechanisms governing β cell homeostasis and insulin secretion are incompletely understood. This study aims to elucidate the role of Ral-GTPase activating protein (RalGAP) complexes in β cell homeostasis and insulin secretion.
Keywords:
apoptosis
insulin
RalGAPβ
type 2 diabetes
β cells
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