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Design of complex neuroscience experiments using mixed-integer linear programming
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DOI：10.1016/j.neuron.2021.02.019.png)
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Abstract
En 中文
Over the past few decades, neuroscience experiments have become increasingly complex and naturalistic. Experimental design has in turn become more challenging, as experiments must conform to an everincreasing diversity of design constraints. In this article, we demonstrate how this design process can be greatly assisted using an optimization tool known as mixed-integer linear programming (MILP). MILP provides a rich framework for incorporating many types of real-world design constraints into a neuroscience experiment. We introduce the mathematical foundations of MILP, compare MILP to other experimental design techniques, and provide four case studies of how MILP can be used to solve complex experimental design challenges.
Keywords:
FMRI
CORTEX
OBJECT
TASK
MRI
REPRESENTATION
PERCEPTION
MECHANISMS
ATTENTION
FRAMEWORK
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